I suggest you hold yo' breath 'til ain't none left
Yo that's the difference

from Dr. Dre (Ft. Eminem & Xzibit) – What's the Difference Lyrics on Rap Genius

Meaning

Xzibit wants you to “ghost” yourself to death

“Ghosting a hit” of marijuana means to hold it in until no smoke comes out when you exhale

Suffocation, in general, is supposed to be the most euphoric way to commit suicide. Suffocating on weed smoke is heaven, basically..

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