When you spitting real shit eventually you throw up

from Childish Gambino – Life: the biggest troll [andrew auernheimer] Lyrics on Rap Genius

Meaning

When you’re talking about the world, eventually you’re going to realize how fucked up everything is and feel sick because of it. Life is scary and Gambino admits that.

Also on a less complex level he is saying he is a “sick” rapper.

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