Fuck it, I'll blame E
Fuck, I'll blame this smoke
Fuck, I'll blame this dro

from PARTYNEXTDOOR – I Don't Lyrics on Rap Genius

Meaning

He’s blaming Ectasy and Marijuana for the way he’s behaving
Dro refers to hydroponically grown marijuana; high grade"homegrown".

Alternatively, he could be blaming those things for his ex’s behavior

To help improve the meaning of these lyrics, visit “I Don't” by PARTYNEXTDOOR Lyrics and leave a comment on the lyrics box