Th-th-the way that I rhyme, blow nigga's mind
Like the first time you heard Mary J and you were standing in line

from Game (Ft. Common) – Angel Lyrics on Rap Genius

Game compares his rhymes effect on people to that of Mary J Blige’s singing.

This could also be taken as a reference to a person’s first encounter with weed. let’s face it, the first time you get high…it blows your mind

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