Living in a city where the skinny niggas die

from Game (Ft. Kendrick Lamar) – The City Lyrics on Rap Genius

Meaning

Paying homage to 2Pac’s Death Around the Corner:

I see death around the corner, gotta stay high while I survive in the city where the skinny niggas die.

Tupac uses this line in more than one song like he does with other sayings of his. A line in Pac’s Straight Ballin':

And they say, ‘How do you survive weighing 165
In the city where the skinny niggas die?’

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