I gotta drink my medicine to cover what's inside of me
I'm still fucked up from the days nobody liked me
I'm lying just a little when I say that I don't give a fuck
You know I gotta give a fuck

from Childish Gambino – What The Fuck Are You? (Colouring of Pigeons) Lyrics on Rap Genius

Meaning

His alcohol is his medicine, it makes him forget/feel better about the days when he got bullied. In a way, saying a rap trope like “fuck the world” still acknowledges that you care about the world enough for it to get you that worked up

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