But I can make 'em put their hands in the sky for you

from Jay Z (Ft. Kanye West & Mr. Hudson) – Why I Love You Lyrics on Rap Genius

Meaning

Jay can at least certainly get everyone hyped for the music of his friends.

Also a reference to Do It Again (Put Your Hands Up) a song from Vol 3…Life and Times of S. Carter, featuring Beanie Sigel, making the verse’s target more obvious

May also be another religious reference. In many churches, if people are truly inspired by a song, they will put their hands to the sky and close their eyes in worship.

Jay is saying that he can make the artists on his label worshiped

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