And the gang signs get thrown up

from Mr. Muthafuckin eXquire (Ft. Danny Brown, Das Racist, Despot & El-P) – The Last Huzzah (Remix) Lyrics on Rap Genius

Meaning

Reference to the Kanye West song “We Major”.

Projects to' up, gang signs is thrown up
Niggas hats broke off, that’s how we grow up

The line was also referenced to in Kendrick Lamar’s song “M.A.A.d city.

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