So dope you overdose

from Kanye West (Ft. Jay Z) – Illest Motherfucker Alive Lyrics on Rap Genius

Meaning

A double entendre on “dope”.

“Dope” is slang for either marijuana or heroin, depending on who you’re talking to. Stoners usually call heroin ‘dope’ whereas people who don’t do drugs often call marijuana ‘dope’.

“Dope” also describes how awesome something is.

Basically saying that his level of awesomeness can kill you.

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