I got my gun in my boo purse
And I don't bust back, because I shoot first

from Lil Wayne (Ft. Drake) – Right Above It Lyrics on Rap Genius

Meaning

He packs heat in public, hiding it in his girls hand bag, he’s not hesitant to fire the first shots and take you out.

Suggesting he is never second best, because he “shoots first”, or makes the first move.

A subtle reminder of how Waynes' innovation once changed the rap game.

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