This ain't business, this is personal, bitch
You don't know Xzibit from shit, new school, class dismissed
I had a very fucked up day, I'm needing this fit
Shutting motherfuckers up like they pleadin' the fifth

from Xzibit (Ft. Eminem) – Don't Approach Me Lyrics on Rap Genius

Meaning

To plead the fifth is to refuse to speak under oath, but Xzibit just makes them stop talking completely
– I’m needing this ‘fifth. This .45 or .55 caliber gun.
Or a fifth of liquor

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