You can't sleep cause you're little Cindy Lou Who

from Beastie Boys – B Boys Makin' With the Freak Freak Lyrics on Rap Genius

Meaning

You can’t sleep on his rhymes—just like Cindy Lou Who, a character from Dr. Seuss’s, How the Grinch Stole Christmas. When the Grinch comes down her chimney, she is awake and will NOT go back to sleep.

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