It's heartbreak plus the jetlag
Ohh ohh oh
Heartbreak plus jetlag
Ohh ohh oh
Heartbreak plus jetlag
Ohh

from Frank Ocean – Heartbreak + Jetlag Lyrics on Rap Genius

Meaning

Now he is heartbroken, jetlag is a play on the rest of the song, in which he uses terms about flying, jetlag is the term the refers to when you fly from one time zone to another, getting your sleep and meal times all wrong, you often get hungry in the middle of the night, nad sleepy in the middle of the day.
It could also refer to the fact that now that Frank is well known he flies from a place to another, leaving him with not just his broken heat to deal with, but alsothe jetlag

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