Ladies and gentlemen -- H, to the Izzo

from Jay Z – The Ruler's Back Lyrics on Rap Genius

Meaning

“Izzo (H.O.V.A.)” was the first single off of this record, released the summer before the album. “Izzo” is the E-40-popularized way of saying the letter O. Thus, Jay is beginning to spell out his nickname Hova here, and referencing the chorus of the single, which starts with this phrase.

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