Experiments when needles and skin connect
No wonder where we live is called the projects

from De La Soul – Stakes is High Lyrics on Rap Genius

Meaning

He’s saying that people in his hood are using drugs which are consumed through the use of injections into the bloodstream (for example, heroin). The image of needles entering the skin remind us of science experiments (like drug testing), and so he makes the connection between these experiments and school science projects (pun on “projects”, meaning both the hood and the experiment), like so:

To elaborate, he compares the rampant drug use in some ‘hoods to either human drug trials by pharmaceutical companies, or lab experiments on rats — see the above ’…just animals..‘, and tying that into the dual nick-name for a poor neighborhood: The Projects.

This refers to ‘Government housing projects’, or low-income housing that often becomes infested with crime and drugs, making homes more similar to science projects than actual neighborhoods.

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