Run run run, the crown of our pharaoh
The throne of our queen is empty
Frank hints that the loss of Cleopatra may have serious implications on the Pharaoh and the kingdom at large.
While the historical Cleo never abandoned her post, she did make continually changing alliances with powerful men. After her final alliance with Mark Antony was defeated, she finally abdicated her throne by committing suicide, an event Ocean alludes to later in the song
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