And ya brain jump out the top like Jack-in-the-box

from 50 Cent – Heat Lyrics on Rap Genius

Meaning

A Jack-in-the-box is a children’s toy which is a box with a crank. When you turn the crank a tune will play and when the tune ends the lid will open and a clown will pop out the box. 50 got his aim on your head and will make your brain pop out in a similar fashion.

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