Probably descendants of the Holy Grail
In medieval times, the line of Messianic descent was defined by the French word Sangréal — deriving from the two words Sang Réal, meaning ‘Blood Royal’. This was the Blood Royal of Judah: the kingly line of David which progressed through Jesus and his heirs. In English translation, the definition Sangréal became ‘San Graal’ (as in San Francisco). When written more fully it was ‘Saint Grail’ — the word ‘saint’, of course, relating to ‘holy’. Then, by a natural linguistic process, came the more romantically familiar term, ‘Holy Grail’.
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