Lets talk about the fact you niggas hate I'm up and runnin'
RG3 nigga, be that
Runnin' through this money and these white women
from Pusha T (Ft. French Montana) – Doesn't Matter Lyrics 2 on Rap Genius
Pusha T structures these lines to refer to him and NFL quarterback Robert Griffin III (RG3):
Push is “up and running” in terms of his career, and he’s blowing outrageous amounts of money and getting it in with White chicks. .
RG3 is known for his mobility and above average ability to run the ball for a quarterback. He can also blow money because of his job, and he’s currently engaged to a White chick. .

It is interesting to note that “white girl” is also slang for coke, which Pusha notoriously dealed. So, if he says he is running white women, there is a definite alternative meaning (seeing as runner = dealer)
To help improve the meaning of these lyrics, visit "Doesn't Matter" by Pusha T (Ft. French Montana) Lyrics 2 and leave a comment on the lyrics box