Take some Big and some Pac and you mix em up in a pot
Sprinkle a little Big L on top, what the fuck do you got?
You got the realest and illest killers tied up in a knot
The juggernauts of this rap shit, like it or not

from 50 Cent (Ft. Eminem) – Patiently Waiting Lyrics on Rap Genius

Meaning

The Notorious B.I.G., 2Pac and Big L are all deceased rappers who are often referred to when mentioning the greatest rappers. Mixing these three individuals together would obviously result in a monster and they’d simply be the illest regardless of how you may feel about it. A juggernaut is a term to describe a literal or metaphorical force regarded as unstoppable. The ‘'juggernaut line’‘ was later sampled by Slaughterhouse in ’‘Juggernauts’‘.

The lines were also later sampled in ‘’What Do You Got‘’.

And later in ScHoolboy Q & A$AP Rocky’s ‘’Brand New Guy‘’.

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