We the fam and loyalty never change up
Throughout all of his troubles and all of his fame, his family has stayed the same, as well as the loyalty within it. He could be referring to his actual family or Taylor Gang, his record label/family.
Also, When Wiz and 2 Chainz say that they do it for the “fam” they are referring to the movie —– where a lot of emphasis is put on the Dom’s code which is family first. Anyone that has seen the movie will notice this.
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