Yeah, thinking bout you girl got my mind on E

from Lil Wayne (Ft. John Legend) – So Special Lyrics on Rap Genius

Meaning

Thinking about this girl is like being on Ecstasy

Hopefully, his mind doesn’t act like Peter when he’s on E

It could also mean that he thinks about her so much that his mind is on E as in a car has a full tank and it runs so much that its on E.

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