Here we change your lane, we'll gain a sprain
Change the game

from Cam'ron – More Reasons Lyrics on Rap Genius

Meaning

“Changing lanes” is a double entendre referring to a vehicle on the highway and playing basketball (which Cam'ron and Jim Jones have long done together in Harlem)

In a car, he has nice rims that you can see when he changes lanes but on the basketball court, you can gain a sprain in the “lane” to the hoop

Then the transition from sports talk to drug talk happens in the second double entendre. The phrase “change the game” refers to the way an ankle sprain would affect a outcome and and the way that he wants to begin using the phrase “the game” to discuss the sale of drugs in the upcoming lines

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