Cause if I ain't sharp and heartless, them bitches'll start shit
Excuse me, but this is where we part bitch

from 2Pac – Death Around the Corner Lyrics on Rap Genius

If Pac doesn’t live life dispassionately, acting as if he doesnt give a fuck then people will try to kick dust up on him. So he must stay sharp, so nothing will get started.

This is an exhausting way of living. Sustained heartlessness will rot the soul while paranoia-induced sharpness will tire the brain.

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