Young Frankenstein
See the screws in my head so a nigga won't lose his mind

from L.E.P Bogus Boys (Ft. Lupe Fiasco) – Zombie Land Lyrics on Rap Genius

Meaning

He’s focused (He’s got his head screwed on), presumably on getting money, as can be seen in the next few lines.

Also literally, his head is screwed on like Frankenstein so he’s not going to be losing his head.

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