With it, lyrically niggas never touching us sick
A cell, hard to pass me, I’m too cold they ain’t well
“You can’t touch me” is slang for saying that you are better then someone. “A Single Cell” is a homophone for Sickle-Cell, a disease also known as Sickle-Cell Anemia."
“Hard To Pass Me” is Rapsody again asserting that her high skill level is hard to pass, but also refers to how Sickle-Cell Anemia is a hard disease to pass since it can only be inherited genetically.
“I’m too cool” refers to a common symptom of having Sickle-Cell Anemia in where it causing the person having it to feel cold.
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