Swing down, sweet chariot, stop, and let me ride

from Dr. Dre – Let Me Ride Lyrics on Rap Genius

Meaning

This hook is sampled from the Parliament song “Mothership Connection” which borrows from a classic slave spiritual. Dre’s song was released in the wake of the ‘92 South Central riots

LA Riots
So, this conveys the sense of wanting to get away, while not necessarily having the agency to get away (“Let me”).
Dre, presumably because of his success represents that sort of messiah figure to the “niggas” and “bitches” asking for rides (or ways up outta there).

In a very interesting way, the terminology “Ride” could be dichotomous, illustrating also the propensity for violence which Compton is so associated with. As Dr.Dre is said to be quite deliberate in his production, the same “niggas” and “bitches saying..” are now representative of the legions of those living that life, “Let me Ride” now an acknowledgement, or celebration of the lifestyle.

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