Life is the bitch, and death is her sister
Sleep is the cousin, what a fuckin' family picture
You know Father Time, and we all know Mother Nature
It's all in the family, but I am of no relation

from Lil Wayne (Ft. Cory Gunz) – 6 Foot 7 Foot Lyrics on Rap Genius

Life’s A Bitch (related to life, of course) and sleep is the awkward cousin (reference to Nas' N.Y. State of Mind)

Mother Nature and Father Time are colloquial expressions — in Greek mythology they were personified by Gaia and Cronos.

Wayne finishes off the verse by saying he is unrelated ‘cause, as we know, Wayne ain’t human, also included is a Sideways shout-out to OG sitcom All in the Family, which was famous for bringing issues of race into the American living room.

Also his line “Sleep is the cousin” is taken from Nas’s song ‘New York State of Mind’ where he says “I never sleep ‘cause sleep is the cousin of death.

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