Niggas got a problem Houston!

from Jay Z – What More Can I Say Lyrics on Rap Genius

Meaning

A reference to the Apollo 13 flight, and a pre-emptive shoutout to then-girlfriend Beyonce Knowles.

The line could also be a shot at Marques Houston, who dated Beyonce and appeared in some radio shows at the time to talk shit about Hova and B.

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