"It's time to fight back", that's what Huey said
2 shots in the dark, now Huey's dead

from 2Pac – Changes Lyrics on Rap Genius

Meaning

Refers to Huey P. Newton, founder of the Black Panthers, who was shot dead by a drug dealer in Oakland in 1989 at the age of 47

Huey Newton

(Huey was actually shot three times in the face).

2Pac’s parents were active members of the Black Panther Party. Also refers to the FBI’s history of targeting and monitoring Black and other supposed revolutionary figureheads and implementing strategies to eliminate them by smearing their public image and worse assassinating them — You only have to look at their sister organisation the CIA, who have repeatedly instigated coups and assassinations of International leaders.

Perhaps this is a clever call by 2Pac to reference yet another Huey as well. Huey Long, who did a lot of good things for the people of the state of Louisiana back in the 30’s and was also assassinated.

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