His palms are sweaty, knees weak, arms are heavy
There's vomit on his sweater already: mom's spaghetti

from Eminem – Lose Yourself Lyrics on Rap Genius

Meaning

This verse documents Jimmy “B-Rabbit” Smith, the main character in 8 Mile’s first trip to The Shelter in attempt to rap battle. In the beginning of the movie when he was trying to pump himself up, he ended up puking all over himself in the bathroom.

In context to underground rap battles, these lines quiet deeply define the feeling that MC’s go through before their battle! Eminem in fact used to battle-rap before he was signed and it was a huge way for him to practice and gain popularity.

The lines are really similar to his earlier song “Brain Damage”, although used in a completely different context

My palms were sweaty, And I started to shake at first, Something told me, try to fake a stomach ache it works

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