I'm sick and original
Boy, I gave birth to the first germs

from Jedi Mind Tricks (Ft. Esoteric & Virtuoso) – Death March Lyrics on Rap Genius

Meaning

A double entendre on “sick”, Virtuoso is sick, meaning great at rapping, yet he is also sick with a sickness, hence the next line “I gave birth to the first germs.

Illness is caused by bacteria/germs getting past your immune system and attacking your body, so it would make sense that since Virtuoso is not only sick, but original as well, he would have given birth to the first germs.

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