You're lost as an abandoned dog
Hopsin suggests that these guys have no clue as to how to live their lives — they’ve been abandoned in multiple ways (by their families, society, the government, etc) and thus have become wild and untamed, without anyone to guide them.
To add and expand, this line means that they’re actually very lost as to how things work and as to what is “real” and what is “fake”. He’s essencially saying that this person is lost in his ideas of what is good and bad.
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