And France is enormous you're Lance with endorsements
But you might need a hand to enhance your performance
These two lines tie together with the one before (esp. bike it) as they reference (in-)famous road-racing cyclist Lance Armstrong.
Lupe is saying that you may be successful, but everyone needs a helping hand here and there.
The third reference to Ye (having many ties to Paris' fashion, music), suggesting that he too may need a little help.
Lance participated in the Tour de France and won the tour seven consecutive times. His tremendous success landed him many endorsements. However in 2013 Lance finally confessed to repeatedly using performance-enhancing substances. He lost all of his sponsors and was stripped of his TDF medals.
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