If I cock the thumb, you gotta take a hike to the

from Lupe Fiasco – SLR 3 (Round of Applause) Lyrics on Rap Genius

Meaning

Thumbs up for Lupe wordplay!

“Cock the thumb” is playing off the guns mentioned in the previous line, where one uses their thumb to ready a gun by cocking the hammer. If Lupe cocks the hammer, that’s your cue to take a hike.

Continuing the hand-as-a-gun metaphor, when one makes a “gun” using their hand, the thumb is usually cocked back.

However one also sticks out their thumb when trying to hitchhike — playing off the use of hike in the phrase take a hike and Hitch in the following line.

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